Catechins as antidiabetic compounds of Bridelia ferruginea Benth root bark extract

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Pharmaceutical Characterization of Aqueous Stem Bark Extract of Bridelia ferruginea Benth (Euphorbiaceae)

Purpose: To characterize some preformulation properties of aqueous stem bark extract of Bridelia ferruginea Benth (Euphorbiaceae) (BF). Methods: The stem bark was extracted by maceration in hot distilled water. Two batches of granules containing the extract were prepared by wet granulation using maize starch, polyvinylpyrrolidone (PVP), Avicel PH-101, magnesium stearate, acacia and lactose as e...

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Antifungal Screening of Bridelia ferruginea Benth (Euphorbiaceae) Stem Bark Extract in Mouthwash Formulations

The plant Bridelia ferruginea Benth (Euphorbiaceae) has been known for its use in the management of oral thrush ethnomedicinally in various parts of Africa, a practice which has been justified by results of certain scientific studies. The aim of this study was to develop an appropriate dosage formulation, a mouthwash and evaluate the antifungal potential of this dosage formulation against a maj...

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Chemical Components and Effect on Streptozotocin Induced Diabetes of Bridelia Ferruginea Benth (euphorbiaceae) Root Bark Ethyl Acetate Fraction

The root of Bridelia ferruginea is traditionally used as a treatment for type 2 diabetes. The objective of this study was to evaluate the effect of Bridelia ferruginea root bark ethyl acetate fractions (EA) on streptozotocin-induced diabetes and identify some chemical compounds. Ethyl acetate fraction (25 and 50 mg/kg/day) was administrated to streptozotocin-induced (60 mg/kg) diabetic mice for...

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antifungal screening of bridelia ferruginea benth (euphorbiaceae) stem bark extract in mouthwash formulations

the plant bridelia ferruginea benth (euphorbiaceae) has been known for its use in the management of oral thrush ethnomedicinally in various parts of africa, a practice which has been justified by results of certain scientific studies. the aim of this study was to develop an appropriate dosage formulation, a mouthwash and evaluate the antifungal potential of this dosage formulation against a maj...

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Toxicological evaluation of the aqueous stem bark extract of Bridelia ferruginea (Euphorbiaceae) in rodents

Bridelia ferruginea is a woody shrub that grows in the Savannah or rain forests of Africa and has traditionally been used to treat diabetes, arthritis and boils. Despite all these uses, extensive toxicological evaluation has not been carried out. The aim of the present investigation was to evaluate the sub-chronic toxicological effects of the stem bark aqueous extract of Bridelia ferruginea in ...

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ژورنال

عنوان ژورنال: Journal of Pharmacognosy and Phytotherapy

سال: 2018

ISSN: 2141-2502

DOI: 10.5897/jpp2018.0528